epalons

epalons
Class of neuroactive steroids. Name derived from epiallopregnanolone, an endogenous metabolite of progesterone that has activity on the GABA-A receptor complex. Have anxiolytic, anti-convulsant and sedative-hypnotic properties.

Dictionary of molecular biology. 2004.

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  • neurosteroids — Steroids synthesized in the brain that have effects on neuronal excitability. The epalons may regulate type A GABA receptorsby allosteric potentiation …   Dictionary of molecular biology

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